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Evaluation of anti hyperlipidemic and anti diabetic activity of desmostachyabippinnata extract in experimental animal model

Introduction Hyperlipidemia is a metabolic disorder characterized by elevated concentrations of lipids and lipoproteins in the bloodstream. It is commonly referred to as hypercholesterolemia or hyperlipoproteinemia and represents a major risk factor for cardiovascular diseases worldwide. Lipids, particularly triglycerides (TG), serve as important energy reserves and are either utilized immediately by the body or stored …

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Plant-Based Bioactive Compounds and Their Role in Sustainable Antifungal and Antimicrobial Drug Discovery

1. Introduction Antimicrobial resistance (AMR) has emerged as one of the most serious global public health threats of the twenty-first century. The extensive and uncontrolled use of antibiotics and antifungal drugs has accelerated the evolution of resistant microbial strains, reducing the effectiveness of existing therapeutic agents. According to the World Health Organization (WHO), multidrug-resistant pathogens …

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Medicinal Plant-Based Nanotechnology for Antimicrobial, Antifungal, and Biomedical Applications: Current Progress and Future Perspectives

1. Introduction Nanotechnology has revolutionized modern scientific research through the manipulation of materials at the nanoscale level, generally ranging between 1 and 100 nm. Nanomaterials possess unique physicochemical, optical, catalytic, electrical, and biological properties that differ significantly from their bulk counterparts due to their extremely small particle size and high surface-area-to-volume ratio. These distinctive characteristics …

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Hydrogeochemical Characterisation, Heavy Metal Bioaccumulation in Fish and Aquatic Species, and Public Health Risk Assessment of River Benue, Nigeria

Introduction Freshwater ecosystems play vital roles in sustaining domestic water supply, fisheries, irrigation, transportation, agriculture and biodiversity in many developing countries, including Nigeria. Rivers serve as important ecological and socioeconomic resources for surrounding communities; however, increasing anthropogenic pressure has significantly altered the hydrochemical quality of many aquatic systems. Rapid urbanisation, agricultural runoff, industrial discharge, domestic …

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Phytochemical Extraction and Effects of Solvent on Antimicrobial Potential of Moringa Oleifera Seeds Extracts

1.0 Introduction 1.1 Background of the Study Plants have historically served as rich reservoirs of biologically active compounds exhibiting broad therapeutic properties.MoringaoleiferaLam, known as drumstick tree or miracle tree, has attracted significant scientific research due to its rich reservoir of phytochemicals and broad spectrum antimicrobial. The plant is native to India and is widely cultivated …

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Hemato-biochemical alterations in fish – Cyprinus carpio L. after exposure to ‘Derisom’ a botanical pesticide

Introduction: Since few decadesfreshwater aquatic ecosystems are facing the threat of harmful effects of synthetic pesticides which is creating a major problem to non-target organisms especially fish, which constitutes the major protein source for humans [1]. Much research has been done on plants for the production of environment safe pesticides that can be used both …

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GC-MS based Phytochemical Profiling and Pharmacological Potentials of Annona muricataand Psidium guajava Leaves for Novel Drug Development

1.0 Background of Study Medicinal plants are a valuable reservoir of bioactive compounds with immense pharmaceutical relevance. Globally, more than 60% of therapeutic agents are directly or indirectly derived from natural sources, highlighting the importance of phytochemical research in drug discovery [1,2, 3]. Among the array of medicinal plants, Annona muricata (soursop) and Psidium guajava …

GC-MS based Phytochemical Profiling and Pharmacological Potentials of Annona muricataand Psidium guajava Leaves for Novel Drug Development Read More »

Micellar-Mediated Phosphomolybdic Acid: A Highly Effective Catalyst for the Synthesis of 1,5-Benzodiazepine Derivatives Via A One-Pot Three-Component Reaction

1. Introduction Benzodiazepines constitute an important class of heterocyclic compounds that have attracted considerable attention in medicinal chemistry owing to their broad spectrum of pharmacological activities. These compounds exhibit diverse biological properties, including anticonvulsant, anti-inflammatory, analgesic, hypnotic, sedative, and anxiolytic effects, making them valuable therapeutic agents in modern medicine [1]. In addition to their pharmaceutical …

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Bioplastic Production from Microbial Systems: Progress, Challenges, and Industrial Prospects

1. Introduction The rapid growth in global plastic production over the past several decades has transformed modern society, enabling advancements in packaging, construction, transportation, healthcare, and consumer goods. However, the durability and resistance to degradation that make plastics so useful have also created severe environmental challenges. It is estimated that millions of tons of plastic …

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Evaluating the Repellency and Toxicity of Selected Medicinal Plant Extracts against Sitophilus oryzae Infestation

1. INTRODUCTION Stored grain products, particularly those of economic significance such as rice, wheat, and corn, are highly susceptible to insect infestation, leading to substantial post-harvest losses worldwide. Among the various pests that infest stored grains, Sitophilus oryzae (the rice weevil) stands out as one of the most destructive [1]. This insect species is responsible …

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