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Integrative Naturopathy for Stress, Metabolic Disorders, and Immune Health: A Critical Review

1. Introduction Stress-related disorders and metabolic diseases have become major public health challenges worldwide. Modern lifestyles characterized by unhealthy dietary habits, sedentary behavior, sleep deprivation, environmental pollution, and psychological stress contribute significantly to obesity, diabetes mellitus, cardiovascular disease, hypertension, autoimmune disorders, and impaired immune function. According to the World Health Organization, non-communicable diseases account for …

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Assessment of Heavy Metal Co-Contamination and Antibiotic Resistance Genes in Hospital Wastewater Discharges in Southern Nigeria

1.0 Introduction Hospital wastewater is increasingly recognised as one of the most important environmental reservoirs of chemical and biological contaminants because it receives effluents from diverse healthcare activities, including patient care, surgical procedures, clinical laboratories, diagnostic units, pharmacies, laundries, and intensive care facilities. Unlike municipal wastewater, hospital effluents contain a complex mixture of pharmaceutical residues, …

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Production, Characterization, and Optimization of Pyocyanin from Pseudomonas aeruginosa

1.0. Introduction The increasing demand for pigments in pharmaceutical, food, cosmetic, textile, and biomedical industries has intensified the search for safer and environmentally friendly alternatives to synthetic pigments. Synthetic pigments are widely used because of their stability and availability; however, many have been associated with toxicity, carcinogenicity, environmental pollution, and poor biodegradability (Joshi et al., …

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Bael (Aegle marmelos): A Nutrient-Rich Functional Fruit with Potential to Combat Global Hunger and Malnutrition

Introduction Aegle marmelos (L.) Corrêa, commonly known as bael or Bengal quince, is a medicinally and economically important species belonging to the family Rutaceae. It is native to the Indian subcontinent and is widely distributed throughout South and Southeast Asia. The plant has been revered in traditional Indian systems of medicine for centuries and holds …

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Influence of Seasonal Variation and Solvent Polarity on Bioactive Potential of Selected Terminalia Species

Introduction Oxidative stress, resulting from an imbalance between reactive oxygen species (ROS) generation and antioxidant defense mechanisms, plays a crucial role in the pathogenesis of numerous chronic disorders, including diabetes mellitus, cardiovascular diseases, neurodegenerative conditions, and cancer [23;41] Excessive production of free radicals such as superoxide anions, hydroxyl radicals, and peroxyl radicals can induce lipid …

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Evaluation of anti hyperlipidemic and anti diabetic activity of desmostachyabippinnata extract in experimental animal model

Introduction Hyperlipidemia is a metabolic disorder characterized by elevated concentrations of lipids and lipoproteins in the bloodstream. It is commonly referred to as hypercholesterolemia or hyperlipoproteinemia and represents a major risk factor for cardiovascular diseases worldwide. Lipids, particularly triglycerides (TG), serve as important energy reserves and are either utilized immediately by the body or stored …

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Plant-Based Bioactive Compounds and Their Role in Sustainable Antifungal and Antimicrobial Drug Discovery

1. Introduction Antimicrobial resistance (AMR) has emerged as one of the most serious global public health threats of the twenty-first century. The extensive and uncontrolled use of antibiotics and antifungal drugs has accelerated the evolution of resistant microbial strains, reducing the effectiveness of existing therapeutic agents. According to the World Health Organization (WHO), multidrug-resistant pathogens …

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Medicinal Plant-Based Nanotechnology for Antimicrobial, Antifungal, and Biomedical Applications: Current Progress and Future Perspectives

1. Introduction Nanotechnology has revolutionized modern scientific research through the manipulation of materials at the nanoscale level, generally ranging between 1 and 100 nm. Nanomaterials possess unique physicochemical, optical, catalytic, electrical, and biological properties that differ significantly from their bulk counterparts due to their extremely small particle size and high surface-area-to-volume ratio. These distinctive characteristics …

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Hydrogeochemical Characterisation, Heavy Metal Bioaccumulation in Fish and Aquatic Species, and Public Health Risk Assessment of River Benue, Nigeria

Introduction Freshwater ecosystems play vital roles in sustaining domestic water supply, fisheries, irrigation, transportation, agriculture and biodiversity in many developing countries, including Nigeria. Rivers serve as important ecological and socioeconomic resources for surrounding communities; however, increasing anthropogenic pressure has significantly altered the hydrochemical quality of many aquatic systems. Rapid urbanisation, agricultural runoff, industrial discharge, domestic …

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Phytochemical Extraction and Effects of Solvent on Antimicrobial Potential of Moringa Oleifera Seeds Extracts

1.0 Introduction 1.1 Background of the Study Plants have historically served as rich reservoirs of biologically active compounds exhibiting broad therapeutic properties.MoringaoleiferaLam, known as drumstick tree or miracle tree, has attracted significant scientific research due to its rich reservoir of phytochemicals and broad spectrum antimicrobial. The plant is native to India and is widely cultivated …

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