Original Research Article

Assessment of Heavy Metal Co-Contamination and Antibiotic Resistance Genes in Hospital Wastewater Discharges in Southern Nigeria

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1.0 Introduction Hospital wastewater is increasingly recognised as one of the most important environmental reservoirs of chemical and biological contaminants because it receives effluents from diverse healthcare activities, including patient care, surgical procedures, clinical laboratories, diagnostic units, pharmacies, laundries, and intensive care facilities. Unlike municipal wastewater, hospital effluents contain a complex mixture of pharmaceutical residues, …

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Production, Characterization, and Optimization of Pyocyanin from Pseudomonas aeruginosa

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1.0. Introduction The increasing demand for pigments in pharmaceutical, food, cosmetic, textile, and biomedical industries has intensified the search for safer and environmentally friendly alternatives to synthetic pigments. Synthetic pigments are widely used because of their stability and availability; however, many have been associated with toxicity, carcinogenicity, environmental pollution, and poor biodegradability (Joshi et al., …

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Bael (Aegle marmelos): A Nutrient-Rich Functional Fruit with Potential to Combat Global Hunger and Malnutrition

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Introduction Aegle marmelos (L.) Corrêa, commonly known as bael or Bengal quince, is a medicinally and economically important species belonging to the family Rutaceae. It is native to the Indian subcontinent and is widely distributed throughout South and Southeast Asia. The plant has been revered in traditional Indian systems of medicine for centuries and holds …

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Influence of Seasonal Variation and Solvent Polarity on Bioactive Potential of Selected Terminalia Species

Original Research Article / By

Introduction Oxidative stress, resulting from an imbalance between reactive oxygen species (ROS) generation and antioxidant defense mechanisms, plays a crucial role in the pathogenesis of numerous chronic disorders, including diabetes mellitus, cardiovascular diseases, neurodegenerative conditions, and cancer [23;41] Excessive production of free radicals such as superoxide anions, hydroxyl radicals, and peroxyl radicals can induce lipid …

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Evaluation of anti hyperlipidemic and anti diabetic activity of desmostachyabippinnata extract in experimental animal model

Original Research Article / By

Introduction Hyperlipidemia is a metabolic disorder characterized by elevated concentrations of lipids and lipoproteins in the bloodstream. It is commonly referred to as hypercholesterolemia or hyperlipoproteinemia and represents a major risk factor for cardiovascular diseases worldwide. Lipids, particularly triglycerides (TG), serve as important energy reserves and are either utilized immediately by the body or stored …

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Hydrogeochemical Characterisation, Heavy Metal Bioaccumulation in Fish and Aquatic Species, and Public Health Risk Assessment of River Benue, Nigeria

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Introduction Freshwater ecosystems play vital roles in sustaining domestic water supply, fisheries, irrigation, transportation, agriculture and biodiversity in many developing countries, including Nigeria. Rivers serve as important ecological and socioeconomic resources for surrounding communities; however, increasing anthropogenic pressure has significantly altered the hydrochemical quality of many aquatic systems. Rapid urbanisation, agricultural runoff, industrial discharge, domestic …

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Phytochemical Extraction and Effects of Solvent on Antimicrobial Potential of Moringa Oleifera Seeds Extracts

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1.0 Introduction 1.1 Background of the Study Plants have historically served as rich reservoirs of biologically active compounds exhibiting broad therapeutic properties.MoringaoleiferaLam, known as drumstick tree or miracle tree, has attracted significant scientific research due to its rich reservoir of phytochemicals and broad spectrum antimicrobial. The plant is native to India and is widely cultivated …

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Hemato-biochemical alterations in fish – Cyprinus carpio L. after exposure to ‘Derisom’ a botanical pesticide

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Introduction: Since few decadesfreshwater aquatic ecosystems are facing the threat of harmful effects of synthetic pesticides which is creating a major problem to non-target organisms especially fish, which constitutes the major protein source for humans [1]. Much research has been done on plants for the production of environment safe pesticides that can be used both …

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Micellar-Mediated Phosphomolybdic Acid: A Highly Effective Catalyst for the Synthesis of 1,5-Benzodiazepine Derivatives Via A One-Pot Three-Component Reaction

Original Research Article / By

1. Introduction Benzodiazepines constitute an important class of heterocyclic compounds that have attracted considerable attention in medicinal chemistry owing to their broad spectrum of pharmacological activities. These compounds exhibit diverse biological properties, including anticonvulsant, anti-inflammatory, analgesic, hypnotic, sedative, and anxiolytic effects, making them valuable therapeutic agents in modern medicine [1]. In addition to their pharmaceutical …

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Evaluating the Repellency and Toxicity of Selected Medicinal Plant Extracts against Sitophilus oryzae Infestation

Original Research Article / By

1. INTRODUCTION Stored grain products, particularly those of economic significance such as rice, wheat, and corn, are highly susceptible to insect infestation, leading to substantial post-harvest losses worldwide. Among the various pests that infest stored grains, Sitophilus oryzae (the rice weevil) stands out as one of the most destructive [1]. This insect species is responsible …

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