Abstract:

The global rise in chronic stress, metabolic disorders, and immune-related diseases has increased interest in holistic healthcare approaches that complement conventional medicine. Integrative naturopathy combines evidence-based natural therapies, including nutrition, herbal medicine, hydrotherapy, yoga, meditation, physical activity, sleep optimization, and lifestyle counseling, to improve overall health and quality of life. Chronic psychological stress contributes to metabolic dysfunction, inflammation, insulin resistance, obesity, and impaired immune responses through activation of neuroendocrine pathways. Naturopathic interventions aim to restore physiological balance by addressing the underlying causes of disease rather than only alleviating symptoms. Recent clinical evidence suggests that dietary modification, medicinal plants, probiotics, mindfulness practices, and physical exercise improve metabolic biomarkers, reduce inflammatory mediators, and enhance immune competence. However, variability in study design, treatment protocols, and long-term follow-up limits definitive clinical recommendations. This review critically examines the relationship between stress, metabolism, and immunity, evaluates current evidence supporting integrative naturopathic interventions, discusses their mechanisms of action, and highlights future research priorities for integrating naturopathy into modern healthcare systems.