Abstract:

This study was carried out to examine the antimycotic sensitivity of fungi associated with allergic bronchopulmonary aspergillosis patients towards the antimycotics of Econazole, Itraconazole, and Nystatin. Fifty-two swab samples were collected from patients suffering from bronchopulmonary aspergillosis (ABPA) at the Educational Hospital of Zliten, Libya in the period from January 2022 to July 2022. Fungal isolates included Aspergillus fumigatus, Penicillium sp, Trichophyton sp, Mucor sp, and Bipolris sp representing, 58%, 23%, 12%, 5%, and 2% respectively. Antimycotic sensitivity test results have revealed that the antifungals of Econazole and Itraconazole were the most effective based on the inhibition growth zones diameter of aspergillus sp at 26 mm and 22 mm and Penicillium sp at 23 mm and 18 mm for both antifungals respectively. On the other hand, the antifungal of Nystatin showed the lowest effect on the rest of the isolated fungi as the minimum inhibitory growth zones were at 6 mm and 4.3 mm for Trichophyton sp and Bipolris sp subsequently.